Cancer is a major cause of suffering, disability, death and impoverishment to millions of livelihoods throughout the world 1. In 2020, 19.3 million new cases of cancer were diagnosed worldwide 2,3.

Acquiring a sufficiently powered cohort of control samples matched to a case sample can be time-consuming or, in some cases, impossible. Accordingly, an ability to leverage genetic data from control ...

Whereas cardiovascular disease-related mortality has declined in most developed countries, its known prevalence is increasing worldwide, although few data on the causes of heart disease in the ...