Alexandra Twin has 15+ years of experience as an editor and writer, covering financial news for public and private companies. Natalya Yashina is a CPA, DASM with over 12 years of experience in ...
The normalization of RNA-seq data is essential for accurate downstream inference, but the assumptions upon which most normalization methods are based are not applicable in the single-cell setting.
Comparison of expression data requires normalization. The optimum normalization method depends on sample type, with the most common being to normalize to reference genes. It is critical to select ...