Cryo-electron microscopy (cryo-EM) can help scientists determine the three-dimensional structure of proteins in unprecedented detail. Jacques Dubochet, former group leader at EMBL, shared the 2017 ...

A laser (purple) is powerfully amplified by highly polished mirrors and focused on the electron beam (blue) to shift its phase and increase the cryo-EM microscope’s contrast, allowing biologists to ...

Stretching protein samples in all directions pulls molecules farther apart, allowing them to be visualized using only light ...

How large, fully folded proteins can pass through cell membranes without destroying them has long been one of the open ...

The technology at the center of the growing "resolution revolution" has again shown its value to scientists at Yale by ...