Nature

Nucleophagy removes cytotoxic trapped PARP1

Poly(ADP-ribose) polymerase (PARP) inhibitors (PARPi) induce cytotoxicity in homologous recombination repair (HR)-deficient (HRD) cancers by trapping PARP1 on chromatin, thereby causing irreparable ...
Nature

Single-cell multi-omic atlas and morphogen screening informs midbrain and hindbrain organoid engineering

Patterning of the neural tube establishes midbrain and hindbrain structures that coordinate motor movement, process sensory input and integrate cognitive functions. Cellular impairment within these ...
Politico

EPA won't set nationwide standards for data centers

The Trump administration is not going to set nationwide environmental requirements or recommendations for the rapidly growing data center industry, EPA Administrator Lee Zeldin said Wednesday. While ...
Wall Street Journal

America’s Data-Center Build-Out Is Falling Way Behind Schedule

Tech companies are earmarking unprecedented sums of money to finance the build-out of massive data centers, with a planned $85 billion equity-raise by Google parent Alphabet GOOGL1.17%increase; up ...
The Guardian

‘We should not have to sacrifice’: New York could become first state to temporarily ban large datacenters

Kristen Gonzalez, a state senator who authored the bill, said moratorium would target ‘hyperscale’ datacenters over 20MW New York moved closer toward becoming the first US state to enact a moratorium ...