In oncology, the manipulation of metabolic processes within tumors has surfaced as a pivotal strategy for influencing cancer progression and therapy resistance. Tumor cells often undergo metabolic ...

Background SIRT6 acts as a tumour suppressor in multiple cancers by regulating glucose and lipid metabolism, but its role in intrahepatic cholangiocarcinoma (ICC) remains unclear. Objective We ...

Test time has arrived: the first person has been treated in a highly anticipated gene-therapy trial that aims to coax aged cells to take on a younger identity. The clinical trial is testing an ...

The next step in the youth quest is a technology called chemical reprogramming. The outspoken longevity scientist David Sinclair has been predicting that one day, you’ll go to the doctor and get a ...