Promising mouse studies and billions of dollars in funding are stoking excitement. But we’ve been here before. Earlier this week, Life Biosciences, a biotech company focused on reversing age-related ...

Effects of resorcinol isoprenyl benzene derivative IPI201 on natural killer cell cytotoxicity and tumor cell viability in human colorectal adenocarcinoma cells. An LNP-mRNA–based in vivo cell engager ...

Gear-obsessed editors choose every product we review. We may earn commission if you buy from a link. Why Trust Us? Here’s what you’ll learn when you read this story: A scientist wants to reprogram ...

Yuancheng Ryan Lu could barely breathe while he waited for his labmate to adjust the microscope focus. On the slide in front of them were the results of Lu’s latest attempt to turn back time for ...

Brain fog can be scary. It might appear innocently, like losing your car keys or forgetting what date you scheduled that appointment on. Some of this memory loss is normal—it’s just a natural side ...

Boston-based Life Biosciences is testing whether reprogramming human cells can slow or even reverse the effects of aging. Unsplash Life Biosciences, a Boston-based biotechnology company founded in ...

Metabolic reprogramming in fibrotic lung diseases involves key metabolites like lactate, succinate, and 2-hydroxyglutarate, driving inflammation and fibroblast activation. Lactate accumulation ...

This figure shows primary T cells modified using two approaches. CAR receptors are introduced through targeted DNA insertion (top), while CRISPRoff mRNA and guide RNAs silence additional genes through ...

Aging is the primary risk factor for numerous life-threatening diseases and has long been a central focus of biological research. Epigenetic reprogramming, a process that can modulate cell fate and ...

Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center for Cancer Biology and ...

For those hoping to cure death, and they are legion, a 2016 experiment at the Salk Institute for Biological Studies in San Diego has become liminal — the moment that changed everything. The experiment ...