Nature

Advances in the structures, mechanisms and targeting of molecular chaperones

Molecular chaperones, a class of complex client regulatory systems, play significant roles in the prevention of protein misfolding and abnormal aggregation, the modulation of protein homeostasis, and ...
C&EN

Effect of Lipidation on the Structure, Oligomerization, and Aggregation of Glucagon-like Peptide 1

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Lipidated analogues of glucagon-like peptide 1 (GLP-1) have gained enormous attention ...
Nature

How are cell and tissue structure and function influenced by gravity and what are the gravity perception mechanisms?

It is well documented that cell behavior is also regulated by mechanical cues the cells receive from their microenvironment 1,2. Cells perceive changes in the mechanical properties of their ...
C&EN

Recent Advances and Challenges in Protein Structure Prediction

Artificial intelligence has made significant advances in the field of protein structure prediction in recent years. In particular, DeepMind’s end-to-end model, AlphaFold2, has demonstrated the ...